- Royle Jackson Ltd - Southampton
- RS2-(Electrical Contractors)-Ltd - Southampton
- S G S Roplex Ltd - Southampton
- S W Asgood Engineering Ltd - Southampton
- S+S Inspection Limited - Southampton
- Safetrac Solutions Ltd - Southampton
- Salon Supplies - Southampton
- Seatallan - Southampton
- Security Solutions UK Ltd - Southampton
- Senator Security South Ltd - Southampton
- Sentral IT Ltd - Southampton
- Serba Coatings - Southampton
- Serenity Hygiene - Southampton
- SETA - Southampton
- Shamrock Quay Marina - Southampton
- SHELTER ENVIRONMENTAL - Southampton
- Shelter Environmental Ltd - Asbestos Surveying, Sampling & Management - Southampton
- Shhh engineering ltd - Southampton
- Shop Design & Refit - Southampton
- Shop Services Interiors Ltd - Southampton
- Shoreland Projects - Southampton
- Signblazer - Southampton
- Simplefit Ltd - Southampton
- Siva Group - Southampton
- Snowflake Software - Southampton
- Snows - Southampton
- Solas Marine Ltd - Southampton
- Solent Bathrooms - Southampton
- Solent Environmental Services Asbestos Ltd - Southampton
- Solent Locksmiths Ltd - Southampton
- Solent Tools - SOUTHAMPTON
- Southern Coating Contractors Ltd - Southampton
- Southern Stronghold Ltd - Southampton
- Specialised Polymer Engineering - Southampton
- Spectrum Signs & Work Wear Ltd - Southampton
- SPI Lasers - Southampton
- Spill Consult - Southampton
- Springfield House Care Home - Southampton
- SRF Fire & Security Ltd - Southampton
- Stalwart Products - Southampton
- Stanelco PLC - Southampton
- Stanelco RF Technologies Ltd - Southampton
- Stealth Security S L R S Ltd - Southampton
- StormFlame - Southampton
- Subacoustech - Southampton
- Supertracker - Southampton
- Swiftfix - Southampton
- Switch Live - Southampton
- Symetrica - Southampton
- Syndico Distribution Ltd - Southampton
Companies 301 to 350
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