LTE introduce full control photostability testing
28 April 2009
Drug product testing results can be influenced by several variables and requires careful control during the Photostability testing process.
In addition to illumination sources and exposure levels, the control of temperature and humidity is also essential in order to produce valid photostability testintg results. Temperature increases over the course of testing have been shown to produce an apparent decrease in photostability. Similarly an increase in the relative humidity can also result in a tested drug substance appearing to have poorer photostability than is actually the case.
The 6540 Series Photostability chambers from LTE have been specifically designed to perform near UV and visual light testing with fluorescent lamps in accordance with ICH Q1B Guidelines, Option 2. In addition to precisely controlled lighting levels this second-generation bench top unit also provides complete control over temperature and humidity levels, via an easy to use colour touch-screen interface. Humidity control is achieved through ultrasonic injection and mechanical refrigeration methods whilst the use of a PID controller allows for precise temperature control.
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